STRADB Polyclonal Antibody

STRADB Polyclonal Antibody

Catalog Number:
A001514313RED
Mfr. No.:
RD89921A
Price:
$416
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      • Overview
        • Calculated MW: 21kDa/23kDa/26kDa
          Observed MW: 21kDa

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          Background

          This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein of human STRADB
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          STRADB, ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK, PRO1038 (Gene ID:55437; UniProt:Q9C0K7)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:1000

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