SPRTN Polyclonal Antibody

SPRTN Polyclonal Antibody

Catalog Number:
A001508035RED
Mfr. No.:
RD252495A
Price:
$253
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      • Overview
        • Gene Accession: BC015740

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          Background

          The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human SPRTN
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          C1orf124, CA124, Chromosome 1 open reading frame 124 , DDDL1880, dJ876B10.3, PRO4323, RP5-876B10.3, Spartan, SprT-like domain at the N terminus, SprT-like N-terminal domain, Zinc finger RAD18 domain-containing protein C1orf124 (UniProt:Q9H040)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:50-1:300
          ELISA 1:5000-1:10000

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