Sphingosine-1-Phosphate Receptor 1 - ExpressMAX™ Human GPCR ORF Clones

Sphingosine-1-Phosphate Receptor 1 - ExpressMAX™ Human GPCR ORF Clones

Catalog Number:
MEV1268481CAN
Mfr. No.:
G0571-A; G0571-B; G0571-Plus
Price:
$374
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      • Overview
        • Sphingosine-1-phosphat Receptor 1 is encoded in Humans by the S1PR1 gene, which is highly expressed in endothelial cells. The ligand sphingosine-1-phosphate binds with high affinity. It has been suggested to be involved in the regulation and differentiation of endothelial cells. Activated S1PR1 induces cell-cell adhesion. S1PR1 has been shown to interact with 5-HT1A receptor, GNAI1 and GNAI3.

          Includes:
          ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
          – Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
          Mammalian Transfection Kits (Cat. No. – PLUS)
          – 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
          – 0. 2 mL CANFAST™ Transfection Reagent.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Expression-ready Human GPCR ORF Clones
          Other Properties
          Plasmid size: 6491 bp
          Promoter: pMLV
          ORF Sequence (GenBank based): NM_001400.4
          Protein Sequence (SwissProt): P21453
          Bacterial Selection Antibiotics: Ampicillin
          Mammalian Selection Antibiotic: Neomycin
          Alternative names: EDG1, S1P1, CD363 or ECGF1
          Storage
          ExpressMAX™ GPCR ORF Clones (-20 °C) and CANFAST™ (4 °C).

          * This product is developed, designed and sold exclusively for Research purposes and in vitro use only (RUO). The product was not tested for use in diagnostics or for drug development, nor is it suitable for administration to humans or animals.

      • Applications
        • Application Description
          Functional assays, as protein immobilization, cellular localization and other functional assays.
          High-throughput and large scale protein production and purification.
          Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

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