SPG20 Polyclonal Antibody

SPG20 Polyclonal Antibody

Catalog Number:
A001513642RED
Mfr. No.:
RD88893A
Price:
$416
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      • Overview
        • Observed MW: 104kDa

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          Background

          This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein of human SPG20
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          SPARTIN, TAHCCP1, SPG20, spartin (Gene ID:23111; UniProt:Q8N0X7)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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