SORBS2 Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA

SORBS2 Polyclonal Antibody (1.02 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001507087RED
Mfr. No.:
RD219081A
Price:
$253
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      • Overview
        • Calculated MW: 124 kDa
          Observed MW: Refer to figures
          Gene Accession: BC011883

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          Background

          Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Fusion protein of human SORBS2
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1.02 mg/mL
          Antigen
          Arg binding protein 2, Arg-binding protein 2, Arg/Abl interacting protein 2, Arg/Abl interacting protein, Arg/Abl-interacting protein 2, ArgBP2, KIAA0777, PRO0618, sorbin and SH3 domain containing 2, Sorbin and SH3 domain-containing protein 2, Sorbin, Sorbs2, SRBS2 (UniProt:O94875)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:1000-1:5000
          IHC 1:150-1:300
          ELISA 1:5000-1:10000

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