Sodium Orthovanadate

- Overview
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    Background
    
    Sodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase. Na3VO4 acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by Fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium Orthovanadate is an inhibitor of AK and PFK.
- Properties
  - Alternative Name
    
    trisodium;trioxido(oxo)vanadium
    
    CAS Number
    
    13721-39-6
    
    Molecular Formula
    
    Na3O4V
    
    Molecular Weight
    
    183.91
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in DMSO; insoluble in EtOH; ≥6.7 mg/mL in H2O
    
    Storage
    
    Store at -20°C
    
    * For Research Use Only