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Overview
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Background
SET domain-containing proteins, such as SMYD2, catalyze lysine methylation. Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). It also has methyltransferase activity toward non-histone proteins.
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