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Overview
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Epithelial cadherin (E-cadherin) also known as cadherin-1, is an intercellular adhesion molecule present in epithelial cells. E-cadherin regulates bacterial adhesion to mammalian cells. Deficiencies or loss of function of E-cadherin is associated with cancer progression via increased invasion, metastasis, or proliferation of tumour cells. Anti-E-cadherin stains glandular epithelium, as well as lung, gastrointestinal and ovarian adenocarcinomas. Anti-E-cadherin antibodies raised against E-cadherin and p120 can be used to differentiate ductal and lobular breast cancer. SensiStain Anti-E-cadherin Antibody is created to detect E-cadherin and is a valuable tool for use.
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Overview