Scrambled 10Panx

Scrambled 10Panx

Catalog Number:
L002368439APE
Mfr. No.:
APE-A2701
Price:
$180
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      • Overview
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          Background

          Scrambled 10Panx is the scrambled form of 10Panx (WRQAAFVDSY), a mimetic peptide of pannexin 1 that inhibits dye uptake by macrophages without affecting cellular membrane currents. Being structurally similar to anther peptide PanxE1B, 10Panx is three amino acid shorter but exerting an inhibitory effect against pannexin1 currents in oocytes to a similar extent as PanxE1b. 10Panx is also able to block the activation of I2nd, decrease the bradykinin-induced [Ca2+]i response and attenuate bradykinin-induced ATP release from human fibroblasts loaded with quinacrine. However, in several studies, scrambled 10Panx has been proved to be less effective than 10Panx in its authentic form.

      • Properties
        • Alternative Name
          Scrambled 10Panx Phe-Ser-Val-Tyr-Trp-Ala-Gln-Ala-Asp-Arg
          CAS Number
          1315378-72-3
          Molecular Formula
          C58H79N15O16
          Molecular Weight
          1242.37
          Appearance
          A solid
          Purity
          98.68%
          Solubility
          ≥31.05 mg/mL in DMSO
          Storage
          Store at -20°C

          * For Research Use Only

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