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SARS Spike Mosaic S(M) Protein

SARS Spike Mosaic S(M) Protein

Catalog Number:
P001414547ABE
Mfr. No.:
Abe32-5365
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      • Overview

        • The E. Coli derived 38 kDa recombinant mosaic protein contains the middle section of the Spike protein 408-470, 540-573 amino acids immunodominant regions. SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.

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      • Properties
        • Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          SARS Mosaic protein is >95% pure as determined by 10% PAGE (Coomassie staining).
          Formulation
          25mM Tris-HCl, 0.4% sarcosyl, 0.25% Triton -100 and 50% glycerol.
          Storage
          SARS Mosaic protein is shipped at ambient temperature. Upon arrival, store at -20°C.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          Immunoreactive with sera of SARS-infected individuals. SARS Mosaic Antigen in ELISA and Western blots, excellent antigen for detection of SARS with minimal specificity problems.

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