SARS-CoV-2 NSP8 Polyclonal Antibody(2019-nCoV)

SARS-CoV-2 NSP8 Polyclonal Antibody(2019-nCoV)

Catalog Number:
A001514744RED
Mfr. No.:
RD90437A
Price:
$500
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      • Overview
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          Background

          Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          SARS-COV2
          Immunogen
          Recombinant SARS-CoV-2 NSP8
          Purification
          Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP8
          Conjugate
          Unconjugated
          Formulation
          PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          0.93mg/mL
          Antigen
          Non-structural protein 8, Replicase polyprotein 1a

          * For reference only.

      • Applications
        • Application
          ELISA
        • Application Dilutions
          ELISA 1:4000-1:8000

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