Name: (Sar1,Val5,Ala8)-Angiotensin II
Price: Inquiry

- Overview
  - Saralasin [(Sar1,Val5,Ala8)-Angiotensin II], a peptide compound, is a partial agonist/competitive non-selective antagonist of angiotensin II receptors, though it is commonly mistaken as a competitive antagonist.
    Saralasin's distinction as a partial agonist is based on the fact that
    its therapeutic effect (i.e. reduced hypertension) is only observed in
    patients with high plasma angiotensin II levels, but in patients with
    low angiotensin II levels Saralasin causes hypertension. In other words,
    the effects of Saralasin on the angiotensin II receptor in the absence
    of angiotensin II is pharmacodynamically similar to angiotensin II
    itself thus it is a partial agonist, because if it was an antagonist it
    would not elicit an effect when bound to its receptor. Saralasin is an
    angiotensin II analogue, containing sarcosine-1 and alanine-8, hence the name (sarcosine, alanine, angiotensin).
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Peptides
    
    CAS Number
    
    34273-10-4
    
    Molecular Formula
    
    C42H65N13O10
    
    Molecular Weight
    
    912.05
    
    Purity
    
    ≥98%
    
    Storage
    
    Powder: store in -20°C freezer for up to three years, store in 4°C freezer for up to two years
    In solvent: store in -80°C freezer for up to six months, store in -20°C freezer for up to two months
    
    Shipping
    
    Room temperature (This product is stable at ambient temperature for a few days during ordinary shipping and time spent in Customs)
    
    SMILES
    
    CC([C@H](NC([C@@H](NC(CNC)=O)CCCNC(N)=N)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)C)=O)=O)CC2=CN=CN2)=O)C(C)C)=O)CC3=CC=C(O)C=C3)=O)C
    
    * For research use only

(Sar1,Val5,Ala8)-Angiotensin II

(Sar1,Val5,Ala8)-Angiotensin II

We Also Recommend

(Ser(Ac)7)-Dermorphin

(Ser25)-Protein Kinase C (19-31)

(Ser4,Ile8)-Oxytocin