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Overview
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Calculated MW: 96kDa/101kDa/113kDa/117kDa
Observed MW: 117kDaPlease contact us at for specific academic pricing.
Background
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
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- Properties
- Applications
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Overview