rmFlt3 Ligand Recombinant Protein

rmFlt3 Ligand Recombinant Protein

Catalog Number:
P001412019ABE
Mfr. No.:
Abe32-1209
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • Flt3 Ligand Rhesus Macaque Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids and having a molecular mass of 18.0kDa. The Flt3 Ligand Rhesus Macaque is purified by proprietary chromatographic techniques. FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.

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      • Properties
        • Protein Name
          Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 97.0% as determined by SDS-PAGE.
          Formulation
          Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.
          Storage
          Lyophilized Flt3 Ligand Rhesus Macaque although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Flt3 Ligand Rhesus Macaque should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to reconstitute the lyophilized Flt3 Ligand in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50 as calculated by the dose-dependant stimulation of the proliferation of human AML5 cells is less than 1.0ng/ml, corresponding to a specific activity of 1,000,000IU/mg.

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