Recombinant YTHDF1 Monoclonal Antibody

Recombinant YTHDF1 Monoclonal Antibody

Catalog Number:
A001512041RED
Mfr. No.:
RD86990A
Price:
$392
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      • Overview
        • Calculated MW: 77kDa
          Observed MW: 77kDa

          Please contact us at for specific academic pricing.

          Background

          YTHDF1, also named as YTH domain-containing family protein 1 or C20orf21, is a 559 amino acid protein, which localizes in the cytoplasm. YTHDF1 specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. YTHDF1 acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation. YTHDF1 exists two isoform and calculated molecular weight of isoforms are 61 kDa and 21 kDa.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human; hamster
          Immunogen
          Recombinant protein of human YTHDF1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          300 μg/mL
          Antigen
          C20orf21, DF1 (Gene ID:54915; UniProt:P59326)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:1000-1:2000

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