Name: Recombinant Mouse TNFRSF8/CD30L Receptor/CD30 (C-6His)
Price: Inquiry

- Overview
  - MW : 28.4kD. Recombinant Mouse TNF Receptor Superfamily Member 8 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr281 is expressed with a 6His tag at the C-terminus. CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibodydrug conjugate. Soluble CD30 retains the ability to bind CD30 Ligand and functions as an inhibitor of normal CD30 signaling.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q60846
    
    Gene ID
    
    21941
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Mouse TNFRSF8/CD30L Receptor/CD30 (C-6His)

Recombinant Mouse TNFRSF8/CD30L Receptor/CD30 (C-6His)

More Information

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