Name: Recombinant Mouse IL-23 Receptor/IL-23R (C-Fc)
Price: Inquiry

- Overview
  - MW : 67.3kD. Recombinant Mouse Interleukin-23 Receptor is produced by our Mammalian expression system and the target gene encoding Gly24-Asp372 is expressed with a Fc tag at the C-terminus. Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor beta1 (IL12R beta1) and IL12R beta2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12R beta1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis, multiple sclerosis, Gravess ophtalmopathy and inflammatory bowel diseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q8K4B4
    
    Gene ID
    
    209590
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Mouse IL-23 Receptor/IL-23R (C-Fc)

Recombinant Mouse IL-23 Receptor/IL-23R (C-Fc)

More Information

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