Recombinant Mouse Follistatin-Like 1/FSTL1 (C-6His)

Recombinant Mouse Follistatin-Like 1/FSTL1 (C-6His)

Catalog Number:
P001412499ABE
Mfr. No.:
Abe32-8723
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      • Overview
        • MW : 33.5kD. Recombinant Mouse Follistatin-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Glu19-Ile306 is expressed with a 6His tag at the C-terminus. Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the follistatin family of proteins. FSTL1 is composed of a follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGF beta1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
          Storage
          Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          14314

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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