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Recombinant mouse FAP protein with C-terminal mFc tag

Recombinant mouse FAP protein with C-terminal mFc tag

Catalog Number:
P001417452ABE
Mfr. No.:
Abe32-17159
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      • Overview

        • The protein has a predicted molecular mass of 111.4 kDa after removal of the signal peptide. The apparent molecular mass of Mouse-FAP-mFc is approximately 130 kDa due to glycosylation. This gene belongs to the serine protease family. The encoded protein is an inducible cell-surface bound glycoprotein specifically expressed in tumor-associated fibroblasts and pericytes of epithelial tumors and has protease and gelatinase activity. The protein plays a role in remodeling of the extracellular matrix (ECM) and may affect tumorigenesis and tissue repair. Alternately spliced transcript variants of this gene are described in the literature (PMID 9139873), but the full-length sequence of these variants is not available.

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      • Properties
        • Protein Name
          SIMP, APCE
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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