Name: Recombinant Mouse Ectodysplasin Receptor/EDAR (C-Fc)
Price: Inquiry

- Overview
  - MW : 44.7kD. Recombinant Mouse Ectodysplasin Receptor is produced by our Mammalian expression system and the target gene encoding Glu27-Ile189 is expressed with a Fc tag at the C-terminus. Ectodysplasin A receptor (EDAR) is a type I transmembrane protein of the TNF-a receptor superfamily which plays a key role in ectodermal differentiation. EDAR was encoded by the mouse downless gene and defective in human dominant and recessive forms of autosomal hypohidrotic ectodermal dysplasia (EDA) syndrome. The extracellular domain of EDAR contains 14 cysteine residues, six of which approximate the TNFRSF cysteine-rich region, the cytoplasmic domain contains a region with homology to the death domains found in other TNFRSF members. EDAR has been suggested to be an early and important promoter of placode development in all ectodermal organs, such as uch as hair follicles, teeth and sweat glands. EDA-A1, the A1 isoform of EDA, is the EDAR ligand. EDA and EDA are implicated in appendage development by the cloning of a gene underlying hypohidrotic ectodermal dysplasia (HED) in mouse and human. HED is characterized by agenesis or malformation of ectoderm-derived appendages, such as teeth, sweat glands and hair follicles, while the skin itself develops normally.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q9R187
    
    Gene ID
    
    13608
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Mouse Ectodysplasin Receptor/EDAR (C-Fc)

Recombinant Mouse Ectodysplasin Receptor/EDAR (C-Fc)

More Information

We Also Recommend

Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 (C-6His)

Recombinant Mouse B7-2/CD86 (C-Fc)

Recombinant Mouse IL-7 Receptor Subunit a/IL-7RA/CD127(C-Fc)