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Overview
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MW : 43.4kD. Recombinant Mouse Chitinase-Like Protein 3 is produced by our Mammalian expression system and the target gene encoding Tyr22-Tyr398 is expressed with a 6His tag at the C-terminus. Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.
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Overview