Recombinant Mouse Alpha-1-antitrypsin 1-1/Serpin A1a (C-6His)

Recombinant Mouse Alpha-1-antitrypsin 1-1/Serpin A1a (C-6His)

Catalog Number:
P001411768ABE
Mfr. No.:
Abe32-7584
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      • Overview
        • MW : 44.5kD. Recombinant Mouse Alpha-1-antitrypsin 1-1 is produced by our Mammalian expression system and the target gene encoding Glu25-Lys413 is expressed with a 6His tag at the C-terminus. Alpha-1-antitrypsin 1-3(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          20700

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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