Name: Recombinant Human Vimentin, GST Tag
Price: Inquiry

- Overview
  - Vimentin Human Recombinant GST Tag full length protein is produced in E. Coli, having a molecular weight of 86kDa (determined by SDS gel elctrophoresis). Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines. Vimentin is the main intermediate filament protein in mesenchymal cells and is therefore of value in the differential diagnosis of undifferentiated neoplasms.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Vimentin, Vim, FLJ36605.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    The Vimentin protein solution contains 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Vimentin, GST Tag

Recombinant Human Vimentin, GST Tag

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