Recombinant human VEGFR2 Protein with C-terminal 6×His tag

Recombinant human VEGFR2 Protein with C-terminal 6×His tag

Catalog Number:
P001417579ABE
Mfr. No.:
Abe32-17152
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      • Overview
        • The protein has a predicted molecular mass of 84.1kDa after removal of the signal peptide. The apparent molecular mass of VEGFR2-His is approximately 130-250 kDa due to glycosylation. Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

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      • Properties
        • Protein Name
          CD309, FLK1, VEGFR, VEGFR2
          Source
          HEK293 cells
          Type
          Recombinant Proteins
          Purification
          The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
          Formulation
          Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.
          Storage
          Store at -80°C for 12 months (Avoid repeated freezing and thawing)

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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