Name: Recombinant Human v-yes-1 Yamaguchi Sarcoma Viral Related Oncogene
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- Overview
  - LYN Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 535 amino acids (1-512) and having a molecular mass of 61.0kDa. LYN is fused to a 23 amino acid His-tag at N-terminus. Tyrosine-protein kinase Lyn (LYN) belongs to the src family of non-receptor protein tyrosine kinases, which is primarily expressed in haematopoietic tissues. LYN protein is involved in induction of stress-activated protein kinase (SAPK), but not ERK or p38 MAPK, in response to genotoxic agents. LYN protein stimulates SAPK by a MKK7- and MEKK1-dependent mechanism. The LYN - MEKK1 - MKK7 - SAPK pathway is efficient in the induction of apoptosis by genotoxic agents.
    
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- Properties
  - Protein Name
    
    Tyrosine-protein kinase Lyn, Lck/Yes-related novelprotein tyrosine kinase, V-yes-1 Yamaguchi sarcoma viral related oncogenehomolog, p53Lyn, p56Lyn, JTK8, EC 2.7.10, LYN Proto-Oncogene, Src FamilyTyrosine Kinase, V-Yes-1 Yamaguchi Sarcoma Viral Rel
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    The LYN solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0) , 0.4M urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human v-yes-1 Yamaguchi Sarcoma Viral Related Oncogene

Recombinant Human v-yes-1 Yamaguchi Sarcoma Viral Related Oncogene

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