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Overview
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UTP23 Human Recombinant produced in E. coli is a single polypeptide chain containing 272 amino acids (1-249) and having a molecular mass of 30.8 kDa. UTP23 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.rRNA-processing protein UTP23 homolog (UTP23) is a small subunit (SSU) processome component. The SSU processome is a complex involved in ribosome biogenesis and essential for pre-18S rRNA maturation. UTP23 is vital for the first 3 cleavage steps in 18S rRNA maturation. Furthermore, single-point mutations in the conserved putative active site of Utp24 but not Utp23 annul its function in ribosome biogenesis.
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Overview