Recombinant Human Upstream Transcription Factor 1

Recombinant Human Upstream Transcription Factor 1

Catalog Number:
P001414417ABE
Mfr. No.:
Abe32-5200
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • USF1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 333 amino acids (1-310 a.a) and having a molecular mass of 35.9kDa. USF1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Upstream Transcription Factor 1 (USF1) belongs to the basic helix-loop-helix leucine zipper family, and functions as a cellular transcription factor. USF1 activates transcription via pyrimidine-rich initiator (Inr) elements and E-box motifs. The USF1 gene has been linked to familial combined hyperlipidemia (FCHL). USF1 is a transcription factor which binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in a various viral and cellular promoters.

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      • Properties
        • Protein Name
          Upstream Transcription Factor 1, Class B Basic Helix-Loop-Helix Protein 11, Major Late Transcription Factor 1, bHLHb11, HYPLIP1, FCHL, FCHL1, MLTF, MLTFI, UEF, Upstream Stimulatory Factor 1, BHLHB11, USF, USF1.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE.
          Formulation
          USF1 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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