Name: Recombinant Human U2 Small Nuclear RNA Auxiliary Factor 1
Price: Inquiry

- Overview
  - U2AF1 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 263 amino acids (1-240 a.a) and havinga molecular mass of 30.3kDa. U2AF1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. U2AF1is a member of the splicing factor SR family. U2 auxiliary factor, comprising alarge and a smallsubunit, is a non-snRNP protein essential for the binding of U2 snRNP to thepre-mRNA branch site. U2AF1 is the small subunit which plays a vital role inboth constitutive and enhancer-dependent RNA splicing by directly mediating interactions betweenthe large subunit and proteins bound to the enhancers. U2 small nuclear RNAauxiliary factor 1 (U2AF1) is a protein-coding gene. Among the diseases whichare associated with U2AF1:Myoclonus Epilepsy and progressive Myoclonus Epilepsy.
    
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- Properties
  - Protein Name
    
    Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliaryfactor small subunit, U2AF35, U2AFBP, FP793, RNU2AF1, RN.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    U2AF1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human U2 Small Nuclear RNA Auxiliary Factor 1

Recombinant Human U2 Small Nuclear RNA Auxiliary Factor 1

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