-
-
Overview
-
TSSC4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 353 amino acids (1-329) and having a molecular mass of 36.8 kDa. TSSC4 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TSSC4 is a member of the TSSC4 family. TSSC4 protein is one of quite a few tumor-suppressing subtransferable fragments found in the imprinted gene domain of 11p15.5, a significant tumor-suppressor gene section. Modifications in this section are linked to the Beckwith-Wiedemann syndrome, rhabdomyosarcoma, Wilms tumor, adrenocortical carcinoma, and breast, ovarian, and lung cancer. TSSC4 takes part in malignancies and disease that include this section in addition to hematopoietic cell function. TSSC4 is broadly expressed in virtually all adult tissues, and is found in fetal liver, brain, lung and kidney.
Please contact us at for specific academic pricing.
-
- Properties
-
Overview