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Recombinant Human Ts Translation Elongation Factor, Mitochondrial

Recombinant Human Ts Translation Elongation Factor, Mitochondrial

Catalog Number:
P001414360ABE
Mfr. No.:
Abe32-5146
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  • Size:
    20 µg
    Quantity:
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      • Overview

        • TSFM Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (46-346 a.a) and having a molecular mass of 32.9kDa. TSFM is purified by proprietary chromatographic techniques. TSFM is a mitochondrial translation elongation factor which is linked with the EF-Tu. GDP complex and induces the exchange of GDP to GTP. TSFM stays bound to the aminoacyl-tRNA. EF-Tu. GTP complex until the GTP hydrolysis stage on the ribosome. Mutations in TSFM are related with combined oxidative phosphorylation deficiency-3 syndrome.

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      • Properties
        • Protein Name
          Elongation factor Ts, mitochondrial, Ts Translation Elongation Factor Mitochondrial, TSFM, EF-Ts, EF-TsMt, COXPD3.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          TSFM protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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