Name: Recombinant human TLR3 protein with C-terminal human Fc tag
Price: Inquiry

- Overview
  - The protein has a predicted molecular mass of 122 kDa after removal of the signal peptide. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    CD283; IIAE2
    
    Source
    
    HEK293 cells
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
    
    Formulation
    
    50µg in 200µl sterile PBS, 10% Glycerol
    
    Storage
    
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant human TLR3 protein with C-terminal human Fc tag

Recombinant human TLR3 protein with C-terminal human Fc tag

We Also Recommend

RBP7 Recombinant Protein

Recombinant human TNFRSF1A protein with C-terminal human Fc tag

Recombinant human TYRO3 protein with C-terminal human Fc tag