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Recombinant Human TIMELESS Interacting Protein

Recombinant Human TIMELESS Interacting Protein

Catalog Number:
P001414305ABE
Mfr. No.:
Abe32-5091
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  • Size:
    10 µg
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      • Overview

        • TIPIN Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 324 amino acids (1-301) and having a molecular mass of 36.9kDa. TIPIN is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. TIPIN is a member of the CSM3 family. TIPIN protein is essential for normal advancement of S-phase and vital for cell existence after DNA damage or replication stress. TIPIN is specifically necessary for the ATR - CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

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      • Properties
        • Protein Name
          TIMELESS Interacting Protein, CSM3 Homolog.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          The TIPIN solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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