Recombinant Human Stimulator of Interferon Genes Protein/Sting (N-Sumo-6His)

Recombinant Human Stimulator of Interferon Genes Protein/Sting (N-Sumo-6His)

Catalog Number:
P001411338ABE
Mfr. No.:
Abe32-9542
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      • Overview
        • Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.

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      • Properties
        • Protein Name
          Stimulator of interferon genes protein; TMEM173; Mediator of IRF3 activation; sting
          Source
          E. coli
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of PBS, pH7.4.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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