Recombinant Human Sprouty Homolog 4

Recombinant Human Sprouty Homolog 4

Catalog Number:
P001414164ABE
Mfr. No.:
Abe32-4950
Price:
  • Size:
    25 µg
    Quantity:
    Add to Cart:
      • Overview
        • SPRY4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-299) and having a molecular mass of 34.9 kDa. SPRY4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Sprouty Homolog 4 (SPRY4) is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. SPRY4 is positioned upstream of RAS activation. SPRY4 protein functions include suppressing the insulin receptor and EGFR-transduced MAPK signaling pathway as well as impairing the formation of GTP-Ras.

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      • Properties
        • Protein Name
          Protein sprouty homolog 4, SPRY4, Sprouty Homolog 4, Spry-4, Protein sprouty homolog 4 isoform 2, Sprouty homolog 4 (Drosophila).
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 85.0% as determined by SDS-PAGE.
          Formulation
          The SPRY4 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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