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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptides B & B1

Recombinant Human Small Nuclear Ribonucleoprotein Polypeptides B & B1

Catalog Number:
P001414118ABE
Mfr. No.:
Abe32-4897
Price:
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  • Size:
    10 µg
    Quantity:
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      • Overview

        • SNRPB Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 25,433 Dalton. SNRPB is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques. SNRPB is one of several nuclear proteins which are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the SNRPB protein may also have a role in pre-mRNA splicing or snRNP structure. SNRPB binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. SNRPB functions in the U7 snRNP complex which is involved in histone 3'-end processing.

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      • Properties
        • Protein Name
          Small nuclear ribonucleoprotein-associated proteins B and B', snRNP-B, Sm protein B/B', Sm-B/B', SmB/B', SNRPB, COD, SNRPB1, SmB/SmB'.
          Source
          Sf9 cells
          Type
          Recombinant Proteins
          Purification
          Greater than 80% as determined by SDS-PAGE.
          Formulation
          SNRPB is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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