Recombinant Human SGK1 (N-GST tag)

Recombinant Human SGK1 (N-GST tag)

Catalog Number:
E001278558APP
Mfr. No.:
Z500355
Price:
$672
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • SGK1 is a member of the serum- and glucocorticoid-induced protein kinase that is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol (PI) 3-kinase. SGK1 mRNA is expressed in all tissues and the level of SGK1 mRNA is increased by stimulation with serum or dexamethasone. SGK1 promotes cell survival by phosphorylating and inactivating FKHRL1. SGK and Akt display differences with respect to the efficacy with which they phosphorylate the three regulatory sites on FKHRL1.

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      • Properties
        • Name
          SGK
          Source
          Insect cells
          Type
          Recombinant Proteins
          Formulation
          50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
          Storage
          Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
          Molecular Weight
          73.0 kDa
          Class
          Active Kinases

          * For research use only. Not for diagnostic or therapeutic use.

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