Recombinant Human Selenophosphate Synthase 1/SEPHS1 (C-6His)

Recombinant Human Selenophosphate Synthase 1/SEPHS1 (C-6His)

Catalog Number:
P001412298ABE
Mfr. No.:
Abe32-8471
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      • Overview
        • MW : 43.9kD. Recombinant Human Selenophosphate synthase is produced by our Mammalian expression system and the target gene encoding Met1-Ser392 is expressed with a 6His tag at the C-terminus. Selenophosphate synthetase 1 (SEPHS1) belongs to the selenophosphate synthase 1 family, Class II subfamily. It has four different isoforms by alternative splicing. Isoform 1 and isoform 2 are gradually expressed during the cell cycle until G2/M phase and then decreased, which Isoform 3 is gradually expressed during the cell cycle until S phase and then decreased. SEPHS1 can be activated by phosphate ions and by potassium ions. It can synthesize synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons.

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      • Properties
        • Source
          Human cells
          Type
          Recombinant Proteins
          Formulation
          Supplied as a 0.2 µm filtered solution of 25mM Tris. HCl, pH7.3, 100mM glycine, 10% glycerol.
          Storage
          Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          Gene ID
          22929

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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