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Overview
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SFRP2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 297 amino acids (20-295 a.a) and having a molecular mass of 33.8kDa. SFRP2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Secreted frizzled-relatedprotein 2 (SFRP2) belongs to the SFRP family which contains a cysteine-richdomain homologous to the putative Wnt-binding site of Frizzled proteins. SFRP2function as soluble modulators of Wnt signaling. Methylation of SFRP2 is apossible marker for the existence of colorectal cancer.
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- Properties
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Overview