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Overview
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RWDD1 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 266 amino acids (1-243 a.a.) and having a molecular mass of 30.3kDa (Molecular size on SDS-PAGE will appear higher). RWDD1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. RWD Domain Containing 1 (RWDD1) is a member of the RWDD1/GIR2 family. The RWDD1 protein protects DRG2 (developmentally regulated GTP binding protein 2), from proteolytic degradation. RWD domain refers to 3 signature motifs in proteins: RING finger, WD-repeats, and yeast DEAD (DEXD)-like motif. Current evidence proposes that RWD domain may be required for protein-protein interaction.
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Overview