Name: Recombinant Human Ring Finger Protein 34
Price: Inquiry

- Overview
  - RNF34 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 396 amino acids (1-373a.a) and having a molecular mass of 44.2kDa. RNF34 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. RingFinger Protein 34 (RNF34) has E3 ubiquitin-protein ligase activity. RNF34 has aRINF finger, a motif recognized to be involved in protein-protein and protein-DNAinteractions. RNF34 regulates the levels of CASP8 and CASP10 by targeting themfor proteasomal degradation. In addition, RNF34 protects cells againstapoptosis induced by TNF. RNF34 also binds phosphatidylinositol 5-phosphateandphosphatidylinositol 3-phosphate. Alternatively splicing results in multipletranscript variants encoding distinct isoforms.
    
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- Properties
  - Protein Name
    
    Ring Finger Protein 34, E3 Ubiquitin Protein Ligase, RINGFinger Protein 34, Caspase Regulator CARP1, Caspases-8 And -10-Associated RINGFinger Protein 1, FYVE-RING Finger Protein Momo, Human RING Finger HomologousTo Inhibitor Of Apoptosis Protein
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greaterthan 90.0% as determined by SDS-PAGE.
    
    Formulation
    
    RNF34 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1M NaCl and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Ring Finger Protein 34

Recombinant Human Ring Finger Protein 34

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