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Recombinant Human Regulator of G-Protein Signaling 21

Recombinant Human Regulator of G-Protein Signaling 21

Catalog Number:
P001413883ABE
Mfr. No.:
Abe32-4648
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  • Size:
    20 µg
    Quantity:
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      • Overview

        • RGS21 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 176 amino acids (1-152 a.a.) and having a molecular mass of 20.2kDa. RGS21 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Regulator of G-protein signaling 21 (RGS21) belongs to the RGS family and regulatory molecules which act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS21 protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thus driving them into their inactive GDP-bound form.

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      • Properties
        • Protein Name
          Regulator of G-protein signaling 21, RGS21.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90% as determined by SDS-PAGE.
          Formulation
          RGS21 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.1M NaCl.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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