Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2

Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 2

Catalog Number:
P001413819ABE
Mfr. No.:
Abe32-4583
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • Recombinant RAC2 produced in E. Coli is a single, non-glycosylated polypeptide chain containing 419 amino acids and having a molecular mass of 47 kDa. RAC2 is fused to GST and purified by conventional chromatography techniques. RAC2 is a small signaling G protein/GTPase which is part of the RAS superfamily of small GTP-binding proteins which regulate cell growth, actin cytoskeletal organization, cell proliferation, survival, cell cycle progression, gene transcription rgulation and the activation of protein kinases. RAC2 cycles between an active gtp-bound and inactive gdp-bound state. In active state, RAC2 binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 is involved in the regulation of the nadph oxidase.

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      • Properties
        • Protein Name
          Ras-related C3 botulinum toxin substrate 2, p21-Rac2, Small G protein, GX, RAC2, HSPC022, EN-7.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE.
          Formulation
          The RAC2 protein solution (1mg/ml) contains 1x PBS pH-7.4.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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