Name: Recombinant Human Ras Homolog Gene Family Member Q
Price: Inquiry

- Overview
  - RHOQ Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (1-202 a.a) and having a molecular mass of 24.7kDa. RHOQ is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. RHOQ (rho-related GTP-binding protein RhoQ) is a small signaling G protein which cycles between an active GTP-bound and an inactive GDP-bound state. In the active state it binds to a diversity of effector proteins to regulate cellular responses. Ras-like protein belongs to the Rac subfamily of the Rho family of GTPases. RHOQ is involved in epithelial cell polarization processes. In addition, RHOQ plays a role in CFTR trafficking to the plasma membrane. RHOQ causes the formation of thin, actin-rich surface projections called filopodia.
    
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- Properties
  - Protein Name
    
    ARHQ, RASL7A, TC10, TC10A, Rho-related GTP-binding protein RhoQ, Ras-like protein TC10, Ras-like protein family member 7A, RHOQ.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85% as determined by SDS-PAGE.
    
    Formulation
    
    RHOQ protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 1mM DTT.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Ras Homolog Gene Family Member Q

Recombinant Human Ras Homolog Gene Family Member Q

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