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Recombinant Human RAB5B, Member RAS Oncogene Family

Recombinant Human RAB5B, Member RAS Oncogene Family

Catalog Number:
P001413809ABE
Mfr. No.:
Abe32-4573
Price:
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  • Size:
    20 µg
    Quantity:
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      • Overview

        • RAB5B Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 238 amino acids (1-215 a.a.) and having a molecular mass of 26.1kDa. The RAB5B is purified by proprietary chromatographic techniques. Ras-related protein Rab-5B (RAB5B) belongs to the Rab family of small (monomeric) G proteins. RAB5B is involved in endocytosis and recycling of cell surface molecules. RAB5B interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of RAB5B abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection.

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      • Properties
        • Protein Name
          Ras-related protein Rab-5B, RAB5B.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 90.0% as determined by SDS-PAGE.
          Formulation
          The RAB5B solution (1 mg/ml), 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 20% glycerol and 0.2M NaCl.
          Storage
          RAB5B should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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