Name: Recombinant Human RAB32, Member RAS Oncogene Family
Price: Inquiry

- Overview
  - RAB32 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 249 amino acids (1-225) and having a molecular mass of 27.6 kDa. RAB32 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. RAB32 is a member of the small GTPase superfamily. RAB32 controls ER calcium management and disturbs the specific enhancement of calnexin on the MAM (mitochondria-associated membrane), however avoids affecting the ER distribution of protein-disulfide isomerase and mitofusin-2. Furthermore, RAB32 regulates the targeting of PKA (cAMP-dependent protein kinase) to mitochondrial and ER membranes and by inactivation or overexpression enhances the phosphorylation of Drp1 and Bad. Using a combination of its functions as a regulator of MAM properties and a PKA-anchoring protein, the activity and expression level of RAB32 define the speed of apoptosis onset.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    RAB32 member RAS oncogene family, ras-related protein Rab-32.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 90% as determined by SDS-PAGE.
    
    Formulation
    
    The RAB32 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 0.2M NaCl, 0.2M EDTA and 50% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human RAB32, Member RAS Oncogene Family

Recombinant Human RAB32, Member RAS Oncogene Family

We Also Recommend

Recombinant Human RAB34, Member RAS Oncogene Family

Recombinant Human RAB35, Member RAS Oncogene Family

Recombinant Human RAB3A, Member RAS Oncogene Family