Recombinant Human Purine-Rich Element Binding Protein B

Recombinant Human Purine-Rich Element Binding Protein B

Catalog Number:
P001413773ABE
Mfr. No.:
Abe32-4543
Price:
  • Size:
    20 µg
    Quantity:
    Add to Cart:
      • Overview
        • PURB Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 335 amino acids (1-312) and having a molecular mass of 35.6 kDa. PURB is fused to a 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Purine-Rich Element Binding Protein B (PURB) is a single-stranded DNA-binding protein which takes part in the dendritic transport of a subset of mRNAs. PURB operates as repressor in myoblasts and fibroblasts in the control of vascular smooth muscle alpha-actin gene transcription. PURB binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in various eukaryotes from yeasts through humans.

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      • Properties
        • Protein Name
          Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB, PURBETA.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 95% as determined by SDS-PAGE.
          Formulation
          The PURB solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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