Name: Recombinant human PTP1B protein , 1-321aa
Price: 210.00 USD

- Overview
  - Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Protein tyrosine phosphatase non-receptor type 1, PTPN1, PTP1B, PTP-1B, Protein Tyrosine Phosphatase 1B, EC 3.1.3.48, Protein-tyrosine phosphatase1B, Tyrosine-protein phosphatase non-receptor type 1, Protein tyrosine phosphatase non-receptor type 1, Protein Tyrosine Phosphatase Non Receptor Type-1
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    > 95% by SDS-PAGE
    
    Formulation
    
    Liquid. In 25mM Tris-HCl buffer (pH 7.5) containing 2mM beta-mercaptoethanol, 1mM EDTA1mM DTT, 20% glycerol
    
    Storage
    
    Stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
    
    Concentration
    
    1mg/ml (determined by Bradford assay)
    
    Molecular Weight
    
    37.3 kDa (321aa)
    
    Expression system
    
    E.coli
    
    More Information
    
    UniProt
    
    P18031
    
    * For research use only. Not intended for human, diagnostics or veterinary use.
- Applications
  - Application
    
    SDS-PAGE; Enzyme Activity
- Reference
  - Kimura K, et al. Pyrroloquinoline quinone stimulates epithelial cell proliferation by activating epidermal growth factor receptor through redox cycling. (Free Radic Biol Med. 2012)
    Maeda A, et al. Safranal, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves glucose tolerance in diabetic KK-Ay mice. (Mol Nutr Food Res. 2014)
    Quang TH, et al. Protein Tyrosine Phosphatase 1B Inhibitors from the Roots of Cudrania tricuspidata. (Molecules. 2015)
    Naito Y. et al. Bis(hinokitiolato)zinc complex ([Zn(hkt)2]) activates Akt/protein kinase B independent of insulin signal transduction. (J Biol Inorg Chem. 2016)
    Cho KH, et al. Isolation and structure determination of a new diketopiperazine dimer from marine-derived fungus Aspergillus sp. SF-5280. (Nat Prod Res. 2018)
    Park JS, et al. Furanoaustinol and 7-acetoxydehydroaustinol: new meroterpenoids from a marine-derived fungal strain Penicillium sp. SF-5497. (J Antibiot (Tokyo). 2018)
    VK Thu, Protein tyrosine phosphatase 1B inhibitory triterpene glycosides from Mussaenda pilosissima Valeton. (Phytochemistry Letters. 2020)
    Kim HJ, et al. PTP1B Inhibitory Secondary Metabolites from an Antarctic Fungal Strain Acremonium sp. SF-7394. (Molecules. 2021)

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Recombinant human PTP1B protein , 1-321aa

Recombinant human PTP1B protein , 1-321aa

More Information

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