Name: Recombinant Human Protein N-terminal Glutamine Amidohydrolase/NTAQ1
Price: Inquiry

- Overview
  - MW : 49.8kD. Recombinant Human NTAQ1 is produced by our E.coli expression system and the target gene encoding Met1-Cys205 is expressed with a GST tag at the N-terminus. Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family. WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
    
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- Properties
  - Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of PBS, 100mM GSH, 1% TritonX-100, 15% glycerol, pH7.4.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q96HA8
    
    Gene ID
    
    55093
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Protein N-terminal Glutamine Amidohydrolase/NTAQ1

Recombinant Human Protein N-terminal Glutamine Amidohydrolase/NTAQ1

More Information

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