Name: Recombinant Human Pre-B-Cell Colony-Enhancing Factor 1/PBEF/Visfatin (N-6His)
Price: Inquiry

- Overview
  - MW : 57kD. Recombinant Human Visfatin is produced by our E.coli expression system and the target gene encoding Met1-His491 is expressed with a 6His tag at the N-terminus. Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine visfatin. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are due to its role as a Nampt which can induce angiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1. Extracellular PBEF has been shown to increase inflammatory cytokines, such as TNF-a, IL-1 beta, IL-16, and TGF- beta1. PBEF also increases the production of IL-6, TNF-a, and IL-1 beta in CD14+ monocyctes, macrophages, and dendritic cells, enhances the effectiveness of T cells.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Lyophilized from a 0.2 µm filtered solution of 20mM HEPES, 150mM NaCl, pH8.0.
    
    Storage
    
    Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C for 3 months.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P43490
    
    Gene ID
    
    10135
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Pre-B-Cell Colony-Enhancing Factor 1/PBEF/Visfatin (N-6His)

Recombinant Human Pre-B-Cell Colony-Enhancing Factor 1/PBEF/Visfatin (N-6His)

More Information

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