Name: Recombinant Human Plasma Kallikrein/KLKB1 (C-6His)
Price: Inquiry

- Overview
  - MW : 70.2kD. Recombinant Human Plasma kallikrein is produced by our Mammalian expression system and the target gene encoding Gly20-Ala638 is expressed with a 6His tag at the C-terminus. KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
    
    Please contact us at for specific academic pricing.
- Properties
  - Source
    
    Human cells
    
    Type
    
    Recombinant Proteins
    
    Formulation
    
    Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH8.0.
    
    Storage
    
    Store at -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    P03952
    
    Gene ID
    
    3818
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Recombinant Human Plasma Kallikrein/KLKB1 (C-6His)

Recombinant Human Plasma Kallikrein/KLKB1 (C-6His)

More Information

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